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Non-Biotinylated ANDR(LBD) His&Avi Tag Protein, Human

Non-Biotinylated ANDR(LBD) His&Avi Tag Protein, Human

Catalog Number: UA085086 Brand: UA BIOSCIENCE
Price:
Regular price $665 USD
Regular price Sale price $665 USD
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Product Details

Product Specification


Species Human
Accession P10275-1
Amino Acid Sequence

S663-Q920 with His Tag at the N-Terminus, Avi Tag at the C-Terminus

Expression System E. coli
Molecular Weight 100-120kDa (Reducing)
Purity >95% by SDS-PAGE
Conjugation Unconjugated
Tag His Tag, Avi Tag
Physical Appearance Liquid
Storage Buffer

25mM Hepes,300mM Nacl,10μM DHT,1mM DTT, pH7.5

Reference

Nypaver JR, Barata PC. HLD-0915: Could it be the breakthrough drug we need for metastatic prostate cancer? Expert Opin Investig Drugs. 2026 Aug 29:1-4.
Kargbo RB. Androgen Receptor Protein Degradation in the Treatment of Castration-Resistant Prostate Cancer. ACS Med Chem Lett. 2021 Feb 9;12(3):318-319.

Picture

Bioactivity

The ANDR(LBD) activity was detected using HTRF binding assay. The reaction was performed by incubating the ANDR(LBD) protein, BRD4 and HLD-0915 at room temperature, then reading ratio 665/620 with BMG.

SDS-PAGE

2μg(R:reducing condition, N:non-reducing condition).