Mouse IL-2 Recombinant mAb (SDT-2117-204)
Mouse IL-2 Recombinant mAb (SDT-2117-204)
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | IL-2 |
| Synonyms | Interleukin-2; T-cell growth factor (TCGF); Il-2; Il2 |
| Immunogen | Recombinant Protein |
| Accession | P04351 |
| Clone Number | SDT-2117-204 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Cross Reactivity | No cross-reactivity against mouse IL-4, IL-6, GM-CSF, rat IL-2. |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Interleukin-2 (IL-2) is a cytokine that plays a crucial role in the immune system. It is primarily produced by activated T cells and has multiple functions. Mature mouse IL-2 shares 56% and 73% aa identity with human and rat IL-2, respectively. IL-2 promotes the proliferation and differentiation of T cells, enhancing their ability to fight infections and tumors. It also stimulates the growth and activity of natural killer (NK) cells, which are important for immune defense. Additionally, IL-2 can regulate the activity of regulatory T cells (Tregs), helping to maintain immune tolerance and prevent autoimmune diseases. In clinical settings, IL-2 has been used to treat certain cancers by boosting the immune response, although its use is limited due to potential side effects. Its discovery and research have significantly advanced our understanding of the immune system and provided new strategies for immunotherapy.
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