Mouse IgG Recombinant mAb (SDT-1399-205)
Mouse IgG Recombinant mAb (SDT-1399-205)
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Mouse IgG |
| Clone Number | SDT-1399-205 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Ms |
| Cross Reactivity | No cross reactivity against human IgG, rat IgG |
| Purification | Protein A |
| Concentration | 2mg/ml |
| Purity | ＞95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.09% sodium azide |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Mouse IgG is a monomeric (~150 kDa) immunoglobulin composed of two γ heavy chains (~50–53 kDa, subclass-dependent) paired with two light chains (~25 kDa). It comprises four subclasses—IgG1, IgG2a, IgG2b, and IgG3—with distinct hinge regions and effector functions. Produced by plasma cells following class switching, it dominates the secondary antibody response and constitutes ~80% of total serum Ig. Mouse IgG mediates opsonization, neutralization, ADCC via Fcγ receptor engagement, and classical complement activation with subclass-specific efficiency. Its stability, long half-life, and placental transfer support passive immunity, while membrane-bound mIgG on memory B cells enables rapid recall responses.
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