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Mouse CCL2/JE/MCP-1 Single Plex Kit (Flow Cytometry Bead Assay)

Mouse CCL2/JE/MCP-1 Single Plex Kit (Flow Cytometry Bead Assay)

Catalog Number: S0Q3175 Reactivity: Mouse Conjugation: Brand: Starter
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Regular price $500 USD
Regular price Sale price $500 USD
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Product Details

Product Specification


Antigen CCL2/JE/MCP-1
Reactivity Mouse
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8°C as supplied.

Kit


Precision Intra-assay:;
Inter-assay:
Sample type Serum; Plasma-EDTA; Plasma-Heparin; Plasma-Citrate; Cell Culture Supernatant
Assay type Sandwich (quantitative)
Sensitivity 76.91 pg/mL
Range 38.12 pg/mL-170000 pg/mL
Recovery Serum、plasma and cell culture supernatant: 70%~130%
Assay time 70 minutes
Species reactivity Mouse

Background

Mouse CCL2, also known as JE or MCP-1 (Monocyte Chemoattractant Protein-1), is a cytokine that belongs to the CC chemokine family. It is primarily produced by monocytes, macrophages, and various other cell types in response to inflammatory stimuli. CCL2 plays a crucial role in the recruitment and activation of monocytes, memory T cells, and dendritic cells to sites of inflammation, thereby contributing to the immune response. This protein is involved in various physiological and pathological processes, including the regulation of immune cell migration during inflammation, the development of atherosclerosis, and the progression of certain cancers. Its expression and activity are tightly regulated, and dysregulation of CCL2 has been implicated in numerous diseases, making it a potential target for therapeutic interventions.

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CBA

Protocol Diagram