Mouse CCL2/JE/MCP-1 Recombinant mAb (SDT-1794-123)
Mouse CCL2/JE/MCP-1 Recombinant mAb (SDT-1794-123)
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Mouse CCL2/JE/MCP-1 |
| Synonyms | C-C motif chemokine 2; Monocyte chemoattractant protein 1; Monocyte chemotactic protein 1 (MCP-1); Platelet-derived growth factor-inducible protein JE; Small-inducible cytokine A2; Je; Mcp1; Scya2; Ccl2 |
| Immunogen | Recombinant Protein |
| Accession | P10148 |
| Clone Number | SDT-1794-123 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Ms |
| Cross Reactivity | No cross-reactivity against mouse CXCL14 and mouse MARCO |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Mouse CCL2, also known as JE or MCP-1 (Monocyte Chemoattractant Protein-1), is a cytokine that belongs to the CC chemokine family. It is primarily produced by monocytes, macrophages, and various other cell types in response to inflammatory stimuli. CCL2 plays a crucial role in the recruitment and activation of monocytes, memory T cells, and dendritic cells to sites of inflammation, thereby contributing to the immune response. This protein is involved in various physiological and pathological processes, including the regulation of immune cell migration during inflammation, the development of atherosclerosis, and the progression of certain cancers. Its expression and activity are tightly regulated, and dysregulation of CCL2 has been implicated in numerous diseases, making it a potential target for therapeutic interventions.
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