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LIF Protein, Northern mallard

LIF Protein, Northern mallard

Catalog Number: UA040539 Brand: UA BIOSCIENCE
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$300 USD
$300 USD
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Product Details

Product Specification


Synonyms Leukemia inhibitory factor
Accession A0A493U243
Amino Acid Sequence

Arg25-Ala257 with His Tag at the C-Terminus
Expression System HEK293
Molecular Weight

38-48 kDa (Reducing)
Purity >95% by SDS-PAGE.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, 5% trehalose, pH7.4
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Reference

Nat Biotechnol. 2025 Sep 30.

Background

Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine belonging to the IL-6 family that plays crucial roles in maintaining pluripotency and regulating cell differentiation in avian species. In Anas platyrhynchos (Northern mallard/domestic duck), LIF has been molecularly characterized through cloning studies in related duck species.

LIF protein represents a critical cytokine for stem cell biology, though with species-specific functional distinctions from mammalian systems. While duck ESC derivation primarily relies on ovotransferrin and small molecule inhibitors (Wnt, PKC, ALK inhibitors), LIF serves as an important synergistic factor for enhancing pluripotency and self-renewal in certain culture formulations.

Picture

SDS-PAGE

2μg (R: reducing condition, N: non-reducing condition).