Product Details
Product Details
Product Specification
| Host | Rabbit |
| Immunogen | Recombinant Protein |
| Clone Number | SDT-326-124-2 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | Does not recognize Kappa light chain, Human total IgG |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
There are two types of light chains: kappa and lambda. If a patient has kappa myeloma, their doctor will watch for a rise in the kappa numbers. Likewise, the lambda number will be watched if a patient has lambda myeloma. This can be measured by the Free Light Chain Assay test on a blood or urine specimen. This balance of kappa and lambda together is called the kappa/lambda ratio, which can also indicate a change in levels of disease. The ratio or proportion between the kappa and lambda light chains indicates an excess production of one chain over the other, and therefore can be used as an indication of disease progression or remission.
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