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KIM-1 Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (S-932-2)

KIM-1 Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (S-932-2)

Catalog Number: S0B60166 Application: FCM Reactivity: Hu Conjugation: Alexa Fluor® 647 Brand: Starter
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Regular price $180 USD
Regular price Sale price $180 USD
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Product Details

Product Specification


Host Rabbit
Antigen KIM-1
Synonyms Hepatitis A virus cellular receptor 1; Kidney injury molecule 1 (KIM-1); T-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1); T-cell immunoglobulin mucin receptor 1 (TIM; TIM-1); T-cell membrane protein 1; CD365; KIM1; TIM1; TIMD1; HAVCR1
Immunogen Recombinant Protein
Location Cell membrane
Accession Q96D42
Clone Number S-932-2
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Hu
Positive Sample A549
Purification Protein A
Concentration 1 mg/ml
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.09% sodium azide

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:1000 Hu

Background

KIM-1 is a protein the most highly upregulated in injured kidneys by various types of insults. Its upregulation during renal injury has been found in the kidneys of the vertebrates such as Zebrafish and humans. KIM-1 is also a member of the TIM (T cell transmembrane, immunoglobulin, and mucin) gene family, which plays critical roles in regulating immune cell activity especially regarding the host response to viral infection. It is involved in allergic response, asthma, and transplant tolerance.

Picture

FC

Flow cytometric analysis of KIM-1 expression on A549(Human lung carcinoma epithelial cell). Cells from the A549 (right panel) or Hela (Human cervix adenocarcinoma epithelial cell, left panel) was stained with Alexa Fluor® 647 Rabbit IgG Isotype Control (black line histogram) or SDT KIM-1 Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (red line histogram) at 1:1000 dilution (0.1 μg). Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.