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ITPRIPL1/CD3L1 His Tag Protein, Human

ITPRIPL1/CD3L1 His Tag Protein, Human

Catalog Number: UA016134 Brand: UA BIOSCIENCE
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Regular price $215 USD
Regular price Sale price $215 USD
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Product Details

Product Specification


Species Human
Accession Q6GPH6
Amino Acid Sequence

His25-Gly103 with His Tag at the C-Terminus

Expression System HEK293
Molecular Weight 10-15kDa (Reducing)
Purity >95% by SDS-PAGE & HPLC
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, pH7.4, 5% trehalose

Reference

1. Deng S Y, Zhang Y B, Wang H B, et al. ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion[J]. Cell, 2024, 187(9): 2305-2323.e33.
2. Zou X, Ye W, Wu H, et al. Immune Evasion Mechanism Mediated by ITPRIPL1 and Its Prognostic Implications in Glioma[J]. Brain and Behavior, 2025, 15(8): e70762.
3. Duan W, Tian W, Li Z, et al. A comprehensive pan-cancer analysis revealing the role of ITPRIPL1 as a prognostic and immunological biomarker[J]. Frontiers in Molecular Biosciences, 2024, 11: 1452290.

Picture

SDS-PAGE

2μg (R: reducing condition, N:non-reducing condition).

SEC-HPLC

The purity of ITPRIPL1/CD3L1 His Tag Protein, Human is more than 95% determined by SEC-HPLC.

ELISA

Immobilized ITPRIPL1/CD3L1 His Tag Protein, Human(Cat. No.UA016134) at 1.0μg/mL (100μL/well) can bind Anti-H_ITPRIPL1 mIgG1 Antibody(13B7A6H3) with EC50 of 2.80-3.50 ng/mL.