WB result of Invivo anti-mouse VEGFR-2 Recombinant mAb
Primary antibody: Invivo anti-mouse VEGFR-2 Recombinant mAb at 1/500 dilution
Lane 1: Mouse VEGFR-2/Flk-1/KDR Fc Chimera Protein 0.5 µg
Lane 2: Mouse VEGFR-2/Flk-1/KDR Fc Chimera Protein 1 µg
Secondary antibody: Goat Anti-rat IgG, (H+L), HRP conjugated at 1/1000 dilution
Predicted MW: 150 kDa
Observed MW: 130~180 kDa
Invivo anti-mouse VEGFR-2 Recombinant mAb
Invivo anti-mouse VEGFR-2 Recombinant mAb
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$135 USD
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$135 USD
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Product Details
Product Details
Product Specification
| Host | Rat |
| Synonyms | Vascular endothelial growth factor receptor 2, Fetal liver kinase 1 (FLK-1), Kinase NYK, Protein-tyrosine kinase receptor flk-1, CD309, Kdr, Flk-1, Flk1 |
| Accession | P35918 |
| Clone Number | DC101 |
| Antibody Type | Rat mAb |
| Application | WB, in vivo blocking of VEGF/VEGFR-2 signaling, in vitro blocking of VEGFR signaling |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage |
2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions.
Please avoid repeated freeze-thaw cycles.
|
Dilution
| application | dilution | species |
| WB | 1:500 |
Background
VEGFR-2 protein, also known as Vascular Endothelial Growth Factor Receptor 2 (VEGFR2 or KDR), is a crucial type III receptor tyrosine kinase that plays a pivotal role in regulating angiogenesis, vascular development, permeability, and embryonic hematopoiesis. Specifically, VEGFR-2 is a cell surface receptor for VEGFA, VEGFC, and VEGFD. It actively promotes endothelial cell proliferation, survival, migration, differentiation, and actin cytoskeleton reorganization. Furthermore, VEGFR-2 mediates VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting, which are essential processes in vasculogenesis and angiogenesis.
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Western Blot
