Product Details
Product Details
Product Specification
| Host | Rat |
| Antigen | CD90.2 (Thy-1.2) |
| Synonyms | Thy-1 membrane glycoprotein; Thy-1 antigen; CD90; Thy-1; Thy1 |
| Location | Cell membrane |
| Accession | P01831 |
| Clone Number | S-3680 |
| Antibody Type | Rat mAb |
| Isotype | Rat IgG2b,k |
| Application | FCM, in vivo T cell depletion |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Purity | >95% (Determined by SDS-PAGE) |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 2 to 8 °C for 2 weeks under sterile conditions; |
Background
CD90.2 (Thy-1.2) is a 25-35 kDa glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein and a member of the immunoglobulin superfamily. It is primarily expressed on hematopoietic stem cells, neurons, all thymocytes, and peripheral T cells in mouse strains such as BALB/c, C57BL/6, and C3H. This molecule plays a role in cell adhesion, signal transduction, and the regulation of T cell activation. Additionally, CD90.2 is involved in lymphocyte proliferation and hematopoietic stem cell differentiation. It is also notable for its interaction with CD45 and its potential role in cell-cell interactions during synaptogenesis in the brain.
