Flow cytometric analysis of Mouse CD38 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were labeled with either Rat IgG2a Isotype Control (black line histogram) or SDT Rat Anti-Mouse CD38 antibody (red line histogram) at 1/500 dilution (1 μg). Goat Anti-Rat IgG Alexa Fluor® 488 was used as the secondary antibody. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
Invivo anti-Mouse CD38 Recombinant mAb
Invivo anti-Mouse CD38 Recombinant mAb
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Product Details
Product Details
Product Specification
| Host | Rat |
| Antigen | CD38 |
| Synonyms | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1); Cyclic ADP-ribose hydrolase 1 (cADPR hydrolase 1); Cd38 |
| Location | Membrane |
| Accession | P56528 |
| Clone Number | S-3262 |
| Antibody Type | Rat mAb |
| Isotype | Rat IgG2a,k |
| Application | FCM, in vivo CD38 stimulation, in vitro CD38 stimulation |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Purity | >95% (Determined by SDS-PAGE) |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 2 to 8 °C for 2 weeks under sterile conditions; |
Dilution
| application | dilution | species |
| FCM | 1:500 | Ms |
Background
CD38 is a multifunctional type II transmembrane glycoprotein expressed on immune cells and in various tissues, acting both as a receptor and an enzyme that converts NAD⁺ into cyclic ADP-ribose and ADP-ribose to regulate intracellular calcium signaling, immune cell activation, proliferation, and migration, and is also a key therapeutic target in multiple myeloma due to its high expression on malignant plasma cells and its role in modulating NAD⁺ levels linked to aging and metabolic processes.
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