Invivo anti-Mouse CD317 (BST2, PDCA-1) Recombinant mAb
Invivo anti-Mouse CD317 (BST2, PDCA-1) Recombinant mAb
Product Details
Product Details
Product Specification
| Host | Rat |
| Antigen | CD317 |
| Synonyms | Bone marrow stromal antigen 2; BST-2; HM1.24 antigen; Bst2 |
| Location | Cell membrane |
| Accession | Q8R2Q8 |
| Clone Number | S-3340-1 |
| Antibody Type | Rat mAb |
| Isotype | Rat IgG2b,k |
| Application | FCM, in vivo pDC depletion |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Purity | >95% (Determined by SDS-PAGE) |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 2 to 8 °C for 2 weeks under sterile conditions; |
Background
CD317 protein is a type of protein that plays significant roles in various biological processes. It is a type II transmembrane protein mainly expressed on the surface of cells such as fibroblasts, endothelial and cells some immune cells. One of its key functions is in the regulation of cell proliferation and differentiation. For example, in the bone marrow microenvironment, CD317 protein can influence the growth and development of hematopoietic cells by interacting with other molecules. Moreover, it is involved in the immune response. It can affect the activation and function of immune cells like T cells and B cells, thus participating in the regulation of the body's immune defense mechanism. Additionally, CD317 protein has been found to be associated with some diseases. Abnormal expression of CD317 protein may be related to the occurrence and development of certain cancers and autoimmune diseases. Therefore, research on CD317 protein is of great importance for understanding the mechanisms of cell biology and disease pathogenesis.
