Product Details
Product Details
Product Specification
Host | Human |
Accession | P05231 |
Clone Number | SDT-025-25 |
Antibody Type | Recombinant mAb |
Isotype | Human IgG1 |
Application | Sandwich ELISA |
Reactivity | Hu |
Purification | Protein A |
Concentration | 4 mg/ml |
Purity | >95% by HPLC |
Conjugation | Unconjugated |
Physical Appearance | Liquid |
Storage Buffer | PBS pH7.4 |
Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
application | dilution | species |
Sandwich ELISA | N/A |
Background
Interleukin 6 (IL-6) is a prototypical cytokine for maintaining homeostasis. When homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and contributes to host defense against such emergent stress through activation of acute-phase and immune responses. However, dysregulated excessive and persistent synthesis of IL-6 has a pathological effect on, respectively, acute systemic inflammatory response syndrome and chronic immune-mediated diseases.
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