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IL-28A/IFN-λ2 Recombinant Rabbit mAb (SDT-1616-14)

IL-28A/IFN-λ2 Recombinant Rabbit mAb (SDT-1616-14)

Catalog Number: S0B3345 Application: Sandwich ELISA Reactivity: Hu Conjugation: Unconjugated Brand: Starter
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Regular price $1,500 USD
Regular price Sale price $1,500 USD
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Product Details

Product Specification


Host Rabbit
Antigen IL-28A
Synonyms IL-28A/IFN-λ2
Immunogen Recombinant Protein
Accession Q8IZI9、Q8IZJ0
Clone Number SDT-1616-14
Antibody Type Recombinant mAb
Isotype IgG
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity

No cross-reactivity against human IL-29 and IL-28B, only recognize IL-28A.

Purification Protein A
Concentration 2 mg/ml
Purity >95% by HPLC
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

Interleukin-28A (IL-28A), also known as interferon lambda-2 (IFN-λ2), is a member of the type III interferon family. It is produced in response to viral infections and plays a critical role in the innate immune response. IL-28A exhibits antiviral activity by inducing the expression of interferon-stimulated genes (ISGs) and activating immune cells to inhibit viral replication and spread. IL-28A is primarily expressed by immune cells, such as dendritic cells and macrophages, and acts through the IFN-λ receptor complex to exert its antiviral effects. Due to its role in antiviral defense and immune regulation, IL-28A has garnered significant interest as a potential therapeutic target for viral infections, including hepatitis C and respiratory viruses.

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