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IL-25 Recombinant Rabbit mAb (SDT-615-98)

IL-25 Recombinant Rabbit mAb (SDT-615-98)

Catalog Number: S0B3189 Application: Sandwich ELISA Reactivity: Hu Conjugation: Unconjugated Brand: Starter
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Regular price $1,500 USD
Regular price Sale price $1,500 USD
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Product Details

Product Specification


Host Rabbit
Antigen IL-25
Synonyms IL-17E
Immunogen Recombinant Protein
Accession Q9H293
Clone Number SDT-615-98
Antibody Type Recombinant mAb
Isotype IgG
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity Does not recognize IL-17A, IL-17F
Purification Protein A
Concentration 2 mg/ml
Purity >95% by HPLC
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
Sandwich ELISA N/A

Background

L-17E/IL-25 (Interleukin-25) is a cytokine that belongs to the IL-17 cytokine family. Binding of IL-25 occurs via a heterodimer complex composed of IL-17RB and IL-17RA. The production of IL-25 by injured epithelial cells is an important innate immune signal driving Th2 immune deviation in the subsequent adaptive immune response. IL-25 is an important mediator of allergic reactions and protection against intestinal parasites. IL-25 stimulates release of IL-4, IL-5, and IL-13 from Th2 lymphocytes but, of note, also drives IL-5 and IL-13 secretion from type 2 innate lymphoid cells (ILC2)

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