Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | IL-10 |
| Synonyms | Interleukin-10; IL-10; Cytokine synthesis inhibitory factor (CSIF); IL10 |
| Immunogen | Recombinant Protein |
| Location | Secreted |
| Accession | P22301 |
| Clone Number | SDT-088-59 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | Sandwich ELISA |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Interleukin-10 (IL-10) is a cytokine that plays a crucial role in regulating immune responses. It is primarily produced by various immune cells, including monocytes, macrophages, and regulatory T cells. IL-10 has potent anti-inflammatory properties, as it inhibits the production of pro-inflammatory cytokines such as IL-1, TNF-α, and IFN-γ from activated macrophages and T helper 1 cells. By doing so, it helps to prevent excessive inflammation and tissue damage. Additionally, IL-10 promotes the differentiation of regulatory T cells and enhances the function of B cells, contributing to the maintenance of immune homeostasis. Dysregulation of IL-10 production has been implicated in various diseases, including autoimmune disorders and certain types of cancer, highlighting its importance in both health and disease.
Picture
Picture
Paired Recommendations

