IFN-α 2b Protein, Human
IFN-α 2b Protein, Human
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Regular price
$70 USD
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$70 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Accession | P01563 |
| Amino Acid Sequence | Cys24-Glu188 |
| Expression System | E.coli |
| Molecular Weight | 19kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 50mM Tris, 50mM NaCl, pH8.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
IFN-α is a cytokine that has an immunomodulatory function. It plays an important role not only in antiviral activity but also in several physiologic functions, such as activation of dendritic cells and accelerated expression of major histocompatibility complex I and II molecules that may cause increased antigen presentation. Variants of human leukocyte interferon α 2 (IFN-α 2a, α 2b, and α 2c) differ from each other by changes in their coding regions at nucleotide positions 137 and 170. IFN-α 2b is an important cytokine and used for antiviral and anticancer treatment.
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Bioactivity
Measured by cytotoxicity assay using TF-1cells, the EC50 for this effect is less than 0.5ng/ml.
SDS-PAGE
1μg (R: reducing conditions, N: non-reducing conditions).
