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IFN-α2 His Tag Protein, Human

IFN-α2 His Tag Protein, Human

Catalog Number: UA106004 Brand: UA BIOSCIENCE
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Regular price $170 USD
Regular price Sale price $170 USD
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Product Details

Product Specification


Species Human
Accession P01563
Amino Acid Sequence

Cys24-Glu188, with C-10*His

Expression System HEK293
Molecular Weight Theoretical:20.9kDa Actual:20,24kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Human interferon alpha-2 (IFNα2) is a cytokine belonging to the family of type I IFNs. IFNα2 is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection.IFNα2 was the first subtype to be characterized in the early eighties. As a result, IFNα2 was widely used in basic research to elucidate biological activities, structure and mechanism of action of type I IFNs. IFNα2 was also the first IFN to be produced by the pharmaceutical industry for use as a drug.In addition to their antiviral activity, type I IFNs also inhibit the proliferation of cells and regulate the activation of the immune system.

Picture

SDS-PAGE

2μg(R: reducing conditions)

ELISA

Immobilized Human IFN-α2, His Tag at 4 μg/mL (50 μL/well) can bind Recombinant Human IFNAR2 Protein with EC50 of 0.214-0.257 μg/ ml.