• Human NFL, His tag
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Human NFL, His tag

Human NFL, His tag

Catalog Number: S0A9045 Brand: Starter
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Product Details

Product Specification


Species Human
Synonyms 68 kDa neurofilament protein, Neurofilament triplet L protein, NF68, NFL
Accession P07196
Amino Acid Sequence

Protein sequence (P07196, Ala92-Lys224, with C-10*His) AQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKGGGGSHHHHHHHHHH
Expression System HEK293
Molecular Weight Predicted MW: 17.1 kDa Observed MW: 16.9 kDa
Purity ＞95% by SDS-PAGE
Tag with C-10*His
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution Reconstitute no more than 1 mg/ml according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

Neurofilament light polypeptide, also known as neurofilament light chain, abbreviated to NF-L or Nfl and with the HGNC name NEFL is a member of the intermediate filament protein family. NFL is a biomarker that can be measured with immunoassays in cerebrospinal fluid and plasma and reflects axonal damage in a wide variety of neurological disorders. It is a useful marker for disease monitoring in amyotrophic lateral sclerosis, multiple sclerosis, Alzheimer's disease, and more recently Huntington's disease. It is also promising marker for follow-up of patients with brain tumors.

Picture

SDS-PAGE

2μg（R: reducing conditions）