Product Details
Product Details
Product Specification
Species | Human |
Synonyms | Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25 |
Accession | P01589 |
Amino Acid Sequence |
Protein sequence(P01589, Glu22-Cys213, with C-10*His) ELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSCGGGGSHHHHHHHHHH |
Expression System | HEK293 |
Molecular Weight | Theoretical: 23.4kDa Actual: 35-45kDa |
Purity | >95% by SDS-PAGE |
Conjugation | Unconjugated |
Tag | His Tag |
Physical Appearance | Lyophilized Powder |
Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
Stability & Storage |
12 months from date of receipt, -20℃ to -70℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
IL2RA is a protein that in humans is encoded by the IL2RA gene.Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. Quantification of sIL-2RA is a useful and simple tool for clinicians to assess immune function in vivo as part of the investigation, management, and prognosis of a broad spectrum of diseases, such as sarcoidosis, Multiple Sclerosis, primary biliary cirrhosis, Chronic immune activation in common variable immunodeficiency (CVID), chronic liver diseases and many more.
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Bioactivity

SDS-PAGE


