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Human IL2RA, His Tag

Human IL2RA, His Tag

Catalog Number: S0A4006 Brand: Starter
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Regular price $270 USD
Regular price Sale price $270 USD
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Product Details

Product Specification


Species Human
Synonyms Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25
Accession P01589
Amino Acid Sequence

Protein sequence(P01589, Glu22-Cys213, with C-10*His)

ELCDDDPPEIPHATFKAMAYKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQPVDQASLPGHCREPPPWENEATERIYHFVVGQMVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGEMETSQFPGEEKPQASPEGRPESETSCGGGGSHHHHHHHHHH

Expression System HEK293
Molecular Weight Theoretical: 23.4kDa Actual: 35-45kDa
Purity

>95% by SDS-PAGE

Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20℃ to -70℃ as supplied.

1 month, 2 to 8℃ under sterile conditions after reconstitution.  

Please avoid repeated freeze-thaw cycles. 

Background

IL2RA is a protein that in humans is encoded by the IL2RA gene.Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. Quantification of sIL-2RA is a useful and simple tool for clinicians to assess immune function in vivo as part of the investigation, management, and prognosis of a broad spectrum of diseases, such as sarcoidosis, Multiple Sclerosis, primary biliary cirrhosis, Chronic immune activation in common variable immunodeficiency (CVID), chronic liver diseases and many more.

Picture

Bioactivity

Immobilized human IL-2RA-Fc at 2μg/ml (50μL/well) can bind to IL-2 with a linear range of 0.17ng/ml to 40ng/ml.

SDS-PAGE

2μg (R: reducing conditions)

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