Human IL-13 Single Plex Kit (Flow Cytometry Bead Assay)
Human IL-13 Single Plex Kit (Flow Cytometry Bead Assay)
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$500 USD
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$500 USD
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Product Details
Product Details
Product Specification
| Antigen | IL-13 |
| Reactivity | Human |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8°C as supplied. |
Kit
| Precision | Intra-assay: 2.46%； Inter-assay: 3.01% |
| Sample type | Serum; Plasma; Cell culture supernatant |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 0.15 pg/mL |
| Range | 0.55 - 4500 pg/mL |
| Recovery | 75.53% - 101.13% |
| Assay time | 70 minutes |
| Species reactivity | Human |
Background
IL-13 is a 132-amino-acid nonglycosylated cytokine that shares common features with IL-4. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 bound IL-13 R alpha 2 with high affinity and can directly promote tumor cell invasiveness and the development of tissue fibrosis. Nevertheless, like IL-4, IL-13 inhibits macrophage production of TNF, IL-1β, and pro-inflammatory chemokines, but can upregulate the synthesis of IL-12 by DCs and macrophages.
