Standard curve
Background subtracted standard curve using IL-13 PBS only Pairs in sandwich ELISA. The ELISA was
performed using the components of the corresponding
OneStep kit (S0C3003), which uses the same antibody pair with a different
formulation and format.
Human IL-13 PBS only Pairs Kit
Human IL-13 PBS only Pairs Kit
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$1,115.00 USD
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$1,115.00 USD
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Product Details
Product Details
Product Specification
| Antigen | IL-13 |
Kit
| Range | 3.9 pg/ml - 250 pg/ml |
Background
IL-13 is a 132-amino-acid nonglycosylated cytokine that shares common features with IL-4. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 bound IL-13 R alpha 2 with high affinity and can directly promote tumor cell invasiveness and the development of tissue fibrosis. Nevertheless, like IL-4, IL-13 inhibits macrophage production of TNF, IL-1β, and pro-inflammatory chemokines, but can upregulate the synthesis of IL-12 by DCs and macrophages.
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Picture
ELISA
