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Human IgM Recombinant mAb (SDT-1465-9-1)

Human IgM Recombinant mAb (SDT-1465-9-1)

Catalog Number: S0B3476 Application: CLIA, Sandwich ELISA Reactivity: Hu Conjugation: Brand: Starter
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Regular price $1,500 USD
Regular price Sale price $1,500 USD
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Product Details

Product Specification


Host Rabbit
Antigen Human IgM
Synonyms Immunoglobulin heavy constant mu; Ig mu chain C region; Ig mu chain C region BOT; Ig mu chain C region GAL; Ig mu chain C region OU; IGHM
Location Secreted, Cell membrane
Accession P01871
Clone Number SDT-1465-9-1
Application CLIA, Sandwich ELISA
Reactivity Hu
Cross Reactivity

No cross-reactivity against human IgG, human IgE, mouse serum, rat serum, weak cross-reactivity against human IgA

Concentration 2 mg/ml
Purity >95% by HPLC
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

Human IgM is the first type of antibody produced by the body in response to an initial exposure to an antigen. It is a large, pentameric molecule, composed of five identical Y-shaped units linked together. Each IgM molecule has ten antigen-binding sites, which allows it to be highly effective at agglutinating pathogens. IgM is primarily found in the bloodstream and plays a crucial role in the early stages of the immune response. It can activate the complement system, enhancing the ability to eliminate pathogens. Additionally, the presence of IgM antibodies in diagnostic tests often indicates a recent infection, as it appears earlier than other types of antibodies like IgG.

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