Human IgM Recombinant mAb (SDT-1465-20)
Human IgM Recombinant mAb (SDT-1465-20)
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | Human IgM |
| Synonyms | Immunoglobulin heavy constant mu; Ig mu chain C region; Ig mu chain C region BOT; Ig mu chain C region GAL; Ig mu chain C region OU; IGHM |
| Location | Secreted, Cell membrane |
| Accession | P01871 |
| Clone Number | SDT-1465-20 |
| Application | CLIA, Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross-reactivity against human IgG, human IgE, mouse serum, rat serum, weak cross-reactivity against human IgA |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Human IgM is the first type of antibody produced by the body in response to an initial exposure to an antigen. It is a large, pentameric molecule, composed of five identical Y-shaped units linked together. Each IgM molecule has ten antigen-binding sites, which allows it to be highly effective at agglutinating pathogens. IgM is primarily found in the bloodstream and plays a crucial role in the early stages of the immune response. It can activate the complement system, enhancing the ability to eliminate pathogens. Additionally, the presence of IgM antibodies in diagnostic tests often indicates a recent infection, as it appears earlier than other types of antibodies like IgG.
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