Product Details
Product Details
Product Specification
| Reactivity | Human |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8°C as supplied. |
Kit
| Precision | Intra-assay: <10%; Inter-assay: <20% |
| Sample type | Serum; Plasma; Cell culture supernatant |
| Assay type | Sandwich (quantitative) |
| Sensitivity | <1pg/mL |
| Range | IL-1β:0.15-50000pg/mL;IL-2:0.41-10000pg/mL;IL-4:0.16-4000pg/mL;IL-5:0.68-15000pg/mL;IL-6:0.23-4000pg/mL;IL-8:0.25-30000pg/mL;IL-10:0.78-30000pg/mL;IL-12p70:0.12-30000pg/mL;IL-13:0.35-8000pg/mL;IL-17A:0.27-30000pg/mL;TNF-α:0.76-120000pg/mL;IFN-γ:0.52-15000pg/mL;IFN-α:0.18-15000pg/mL;GM-CSF:0.24-30000pg/mL;MCP-1/CCL2:0.73-4000pg/mL |
| Recovery | Plasma: 70%-130% Serum: 70%-130% Cell culture supernatant: 70%-130% |
| Assay time | 70 minutes |
| Species reactivity | Human |
Background
The Proinflammatory Panel (human) measures fifteen cytokines that are important in inflammatory responses and immune system regulation as well as many other biological processes. These assays can detect secreted biomarkers in a variety of tissues and body fluids where over- or under-expression may indicate a shift in biological equilibrium. This panel also includes assays for many of the Th1/Th2 pathway biomarkers. The Proinflammatory Panel (human) measures biomarkers that are implicated in a number of disorders, including rheumatoid arthritis, Alzheimer disease, asthma, atherosclerosis, allergies, systemic lupus erythematosus,obesity,cancer,depression, multiple sclerosis,diabetes, psoriasis, and Crohn disease. As a result of their association with such a wide spectrum of disease, these biomarkers are the subjects of drug discovery projects and basic research.
