2μg(R: reducing conditions)
HRSV Nucleoprotein , His tag
HRSV Nucleoprotein , His tag
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Product Details
Product Details
Product Specification
| Species | HRSV |
| Synonyms | Protein N, Nucleocapsid protein |
| Accession | P03418 |
| Amino Acid Sequence | Protein sequence(P03418, Met1-Leu391, with C-10*His) MALSKVKLNDTLNKDQLLSSSKYTIQRSTGDSIDTPNYDVQKHINKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTIKILRDAGYHVKANGVDVTTHRQDINGKEMKFEVLTLASLTTEIQINIEIESRKSYKKMLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLTAVIRRANNVLKNEMKRYKGLLPKDIANSFYEVFEKHPHFIDVFVHFGIAQSSTRGGSRVEGIFAGLFMNAYGAGQVMLRWGVLAKSVKNIMLGHASVQAEMEQVVEVYEYAQKLGGEAGFYHILNNPKASLLSLTQFPHFSSVVLGNAAGLGIMGEYRGTPRNQDLYDAAKAYAEQLKENGVINYSVLDLTAEELEAIKHQLNPKDNDVELGGGGSHHHHHHHHHH |
| Expression System | E.coli |
| Molecular Weight | Theoretical:45.1kDa Actual:43kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Respiratory syncytial virus (RSV) is an enveloped, nonsegmented, negative-sense RNA virus in the family Paramyxoviridae. It is the leading cause of acute lower respiratory tract infections (ALRI) in young children and other high-risk populations worldwide. Of the 11 RSV-encoded proteins, N is one of the most conserved structural proteins and is essential for virus encapsidation by coating the entire viral RNA genome to form the ribonucleoprotein (RNP). Although poorly understood, this multifunctional protein was also found to play an important role in viral RNA replication, mRNA transcription, and virus assembly.
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