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HBP His Tag Protein, Human

HBP His Tag Protein, Human

Catalog Number: UA109001 Brand: UA BIOSCIENCE
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$260 USD
$260 USD
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Product Details

Product Specification


Species Human
Synonyms Cationic antimicrobial protein CAP37, Heparin-binding protein (HBP; hHBP)
Accession P20160
Amino Acid Sequence

Ile27-Ala251, with C-10*His
Expression System HEK293
Molecular Weight

Predicted MW: 26 kDa Observed MW: 35-40 kDa
Purity >95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Storage Buffer

0.2M PBS, pH7.4

Reconstitution

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Azurocidin also known as cationic antimicrobial protein CAP37 or heparin-binding protein (HBP) is a protein that in humans is encoded by the AZU1 gene. Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antimicrobial protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. In patients with fever, high plasma levels of HBP indicates that the patient is at high risk of developing sepsis with circulatory collapse.

Picture

SDS-PAGE

2 μg（R: reducing conditions）