2e5 of transient transfected anti- TSLP ScFv CAR-293 cells were stained with 0.5ug FITC-Labeled TSLP His Tag Protein, Human, (Cat. No. UA016092) and unlable respectively (Fig. C and B), and non-transfected 293 cells were used as a control (Fig. A). FITC signal was used to evaluate the binding activity.2e5 of transient transfected anti- TSLP ScFv CAR-293 cells were stained with isotype and Whitlow/218 Linker-Alexa Fluor® 488 (Fig. D and E). Alexa Fluor® 488 signal was used to evaluate the binding activity.
FITC-Labeled TSLP His Tag Protein, Human
FITC-Labeled TSLP His Tag Protein, Human
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Thymic stromal lymphopoietin |
| Accession | Q969D9 |
| Amino Acid Sequence | Tyr29-Gln159 with His Tag at the C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 9-14&18-27kDa (Reducing) |
| Conjugation | FITC |
| Tag | His Tag |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | · 12 months from date of receipt stored at -20 to -80℃. |
| Reference | 1.Kui L, Huang J, Wang G, Zhao J, Wang S, Qin X, Liu L, Hu J, Chen L, Wang X, Li Q, Zhao Y, Tang Y, Xiong K, Zhan S, Ding H, Wang J, Cai H, Zhang Q, Zi X, Deng Q, Gao L, Wang X, Zou C, Yang H, Xiao Y, Yang B, Leng B, Zhang L, Hu G. Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice. Front Immunol. 2025 Oct 22;16:1667195. |
Background
Thymic stromal lymphopoietin (TSLP) is a cytokine secreted by epithelial cells, encoded by a gene that produces a 159-amino acid precursor protein. This protein plays a dual regulatory role in the immune system: on one hand, it promotes type 2 T-helper cell immune responses by activating dendritic cells and directly acts on immune cells such as basophils, driving the development of allergic diseases like atopic dermatitis and asthma; on the other hand, it is involved in maintaining intestinal homeostasis and central immune tolerance. Due to its central role in allergic diseases, TSLP has become an important therapeutic target for conditions such as atopic dermatitis and asthma.
Guidelines
Please strictly follow the recommended dosage for experiments. If the population clustering is not distinct, the recommended dosage may be appropriately increased by 2-5 folds.
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