FITC-Labeled CEACAM-5/CD66e Fc Chimera Protein, Human
FITC-Labeled CEACAM-5/CD66e Fc Chimera Protein, Human
Product Details
Product Details
Product Specification
| Species | Human |
| Antigen | CEACAM-5/CD66e |
| Synonyms | CEA, Meconium antigen 100 |
| Accession | P06731 |
| Amino Acid Sequence | Lys35-Ala685, with C-terminal Human IgG1 Fc |
| Expression System | HEK293 |
| Molecular Weight | CEA, Meconium antigen 100 |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | FITC |
| Tag | Human Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Hammarstrom S. (1999). The carcinoembryonicantigen (CEA) family: structures, suggested functions and expression in normaland malignant tissues. Seminars in Cancer Biology. 9(2): 67-81. |
Background
Thehuman CEA family has been fully characterized. It comprises 29 genes of which18 are expressed; 7 belonging to the CEA subgroup and 11 to the pregnancyspecific glycoprotein subgroup. CEA is an important tumor marker for colorectaland some other carcinomas. The CEA subgroup members are cell membraneassociated and show a complex expression pattern in normal and canceroustissues with notably CEA showing a selective epithelial expression. Several CEAsubgroup members possess cell adhesion properties and the primordial member,biliary glycoprotein, seems to function in signal transduction or regulation ofsignal transduction possibly in association with other CEA sub-family members.
Picture
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Bioactivity
SDS-PAGE
