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FITC Armenian hamster Anti-Mouse TCR β Antibody (S-R616)

FITC Armenian hamster Anti-Mouse TCR β Antibody (S-R616)

Catalog Number: S0B1803 Application: FCM Reactivity: Mouse Conjugation: FITC Brand: Starter
Price:
Regular price $72.00 SGD
Regular price Sale price $72.00 SGD
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Product Details

Product Specification


Host Armenian hamster
Antigen Mouse TCR β
Synonyms T-cell receptor beta-1 chain C region
Location Membrane
Accession P01852
Clone Number S-R616
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse splenocytes
Purification Protein G
Concentration 0.05mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5 μl per million cells in 100μl volume Ms

Background

The TCR β (T-cell receptor beta chain) is a crucial component of the T-cell receptor, which, together with the TCR α chain, forms the αβTCR on the surface of T cells. This receptor is responsible for recognizing and binding to antigenic peptide complexes presented by MHC molecules. The diversity of the TCR β chain is generated through a combination of random recombination of multiple germline gene segments, gene rearrangement, junctional diversity, N-region nucleotide insertions, and random pairing of α and β chains. These mechanisms collectively provide the TCR repertoire with immense diversity, enabling T cells to recognize a wide range of antigens.

Picture

FC

Flow cytometric analysis of TCR β expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with SDT FITC Armenian Hamster Anti-Mouse TCR β Antibody at 0.25 μg/test and either Alexa Fluor® 647 Rat Anti-Mouse CD8a Antibody (Left panel) or Brilliant Violet 421™ Rat Anti-Mouse CD4 Antibody (Right panel). Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.

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