2μg (R: reducing condition, N: non-reducing condition).
Endothelin B Receptor His Tag Protein, Human
Endothelin B Receptor His Tag Protein, Human
Price:
Regular price
$360 USD
Regular price
Sale price
$360 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | ABCDS, ET-B, ET-BR, ETB, ETB1, ETBR, ETRB, HSCR, HSCR2, WS4A |
| Accession | NP_000106.1 |
| Amino Acid Sequence | Glu27-Lys101 with His Tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 15-28kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & SEC-HPLC |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | Maguire, J. J. & Davenport, A. P. Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12. Br. J. Pharmacol. 171, 5555–5572 (2014) |
Background
Endothelin receptors, specifically ETA and ETB, are class A G protein-coupled receptors (GPCRs) that are activated by the vasoactive peptide endothelins and play a role in blood pressure regulation. Selective signaling through the ETB receptor induces vasorelaxation, making selective ETB agonists potential candidates for improved anti-tumor drug delivery and neuroprotection.
Picture
Picture
SDS-PAGE
SEC-HPLC
The purity of Endothelin B Receptor His Tag Protein, Human is more than 95% determined by SEC-HPLC.
ELISA
Immobilized Endothelin B Receptor His Tag Protein, Human (Cat. No. UA011142) at 2.0μg/mL (100μL/well) can bind EDNRB Rabbit pAb with EC50 of 6.38-8.77ng/mL.
