WB result of DCBLD2 Recombinant Rabbit mAb
Primary antibody: DCBLD2 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: A549 whole cell lysate 20 µg
Lane 2: HCC827 whole cell lysate 20 µg
Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 85 kDa
Observed MW: 120 kDa
DCBLD2 Recombinant Rabbit mAb (S-3292-46)
DCBLD2 Recombinant Rabbit mAb (S-3292-46)
Price:
Regular price
$100 USD
Regular price
Sale price
$100 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | DCBLD2 |
| Synonyms | Discoidin, CUB and LCCL domain-containing protein 2; CUB; LCCL and coagulation factor V/VIII-homology domains protein 1; Endothelial and smooth muscle cell-derived neuropilin-like protein; CLCP1; ESDN |
| Immunogen | Synthetic Peptide |
| Accession | Q96PD2 |
| Clone Number | S-3292-46 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu, Mk |
| Positive Sample | A549, HCC827, U-2 OS, A375, HT-1080, PC-3, COS-7 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Mk |
Background
DCBLD2 (Discoidin, CUB and LCCL domain-containing protein 2) is a type-I transmembrane scaffolding receptor encoded on chromosome 3q12.1 that contains extracellular CUB, LCCL and coagulation factor V/VIII homology domains, seven conserved intracellular YxxP phosphorylation motifs, and a C-terminal PDZ-binding motif, enabling it to act as a multi-functional platform coupling receptor tyrosine kinases (e.g., EGFR) or non-receptor tyrosine kinases (e.g., Src, Abl) to downstream signaling cascades such as TRAF6-Akt, focal-adhesion/ITGB1-FAK and CRKL pathways, thereby regulating vascular endothelial and smooth-muscle-cell proliferation, angiogenesis, epithelial-to-mesenchymal transition, tumor growth, metastasis and chemo-resistance, while its circulating levels correlate negatively with lung function and its genetic variants can produce multisystem developmental disorders.
Picture
Picture
Western Blot
WB result of DCBLD2 Recombinant Rabbit mAb
Primary antibody: DCBLD2 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: U-2 OS whole cell lysate 20 µg
Lane 2: A375 whole cell lysate 20 µg
Lane 3: HT-1080 whole cell lysate 20 µg
Lane 4: PC-3 whole cell lysate 20 µg
Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 85 kDa
Observed MW: 120 kDa
This blot was developed with high sensitivity substrate
WB result of DCBLD2 Recombinant Rabbit mAb
Primary antibody: DCBLD2 Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: COS-7 whole cell lysate 20 µg
Secondary antibody: Goat Anti- rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 85 kDa
Observed MW: 120 kDa
This blot was developed with high sensitivity substrate
