WB result of CTGF Recombinant Rabbit mAb
Primary antibody: CTGF Recombinant Rabbit mAb at 1/1000 dilution
Lane 1: MCF7 whole cell lysate 20 µg
Lane 2: HT-1080 whole cell lysate 20 µg
Lane 3: HepG2 whole cell lysate 20 µg
Lane 4: PANC-1 whole cell lysate 20 µg
Negative control: MCF7 whole cell lysate
Secondary antibody: Goat Anti-rabbit IgG, (H+L), HRP conjugated at 1/10000 dilution
Predicted MW: 36 kDa
Observed MW: 36 kDa
CTGF Recombinant Rabbit mAb (S-3356)
CTGF Recombinant Rabbit mAb (S-3356)
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$100 USD
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Product Details
Product Details
Product Specification
| Host | Rabbit |
| Antigen | CTGF |
| Synonyms | CCN family member 2; Cellular communication network factor 2Imported; Connective tissue growth factor; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8 (IBP-8; IGF-binding protein 8; IGFBP-8); HCS24; IGFBP8; CCN2 |
| Location | Secreted |
| Accession | P29279 |
| Clone Number | S-3356 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB |
| Reactivity | Hu |
| Positive Sample | HT-1080, HepG2, PANC-1 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Hu |
Background
Connective tissue growth factor (CTGF, also termed CCN2) is a 38 kDa, cysteine-rich, secreted matricellular protein of the CCN family that orchestrates cell adhesion, migration, proliferation, differentiation, angiogenesis, and extracellular matrix (ECM) remodeling by binding integrins, heparan sulfate proteoglycans, and growth factors such as TGF-β and VEGF through its four conserved domains (IGFBP, VWC, TSP-1, and cysteine-knot CT); physiologically it is indispensable for embryonic skeletal, pancreatic, ovarian, and vascular development, whereas dysregulated CTGF drives fibrosis, diabetic retinopathy, atherosclerosis, and tumorigenesis, making it a prominent therapeutic target now being pursued with monoclonal antibodies in pre-clinical and clinical trials.
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Picture
Western Blot
