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CD6 His Tag Protein, Human

CD6 His Tag Protein, Human

Catalog Number: UA011258 Brand: UA BIOSCIENCE
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Regular price $196 USD
Regular price Sale price $196 USD
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Product Details

Product Specification


Species Human
Synonyms TP120, T12
Accession P30203
Amino Acid Sequence

His18 - Glu398 with His Tag at C-terminus

Expression System HEK293
Molecular Weight 80-95 kDa(reducing)
Purity >95% by SDS-PAGE & > 90% by SEC-HPLC
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS PH7.4 5% trehalose

Stability & Storage

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Reference

Wang X, Zhang Y, Xu X, Liu X, Zhang B. Causal relationship between circulating cytokines and myelodysplastic syndrome: a Mendelian randomization study. Hematology.2025Dec;30(1):2541447. Li Z, Jia L, Huai S. Circulating Inflammatory Proteins Mediate the Causal Effect of Gut Microbiota on Inflammatory Bowel Disease: Bayesian and Mediated Mendelian Randomization. FASEB Bioadv. 2025 Jul 10;7(7):e70039.

Background

CD6 (Cluster of Differentiation 6) is a cell-surface glycoprotein of the scavenger receptor cysteine-rich superfamily that acts as both a costimulatory molecule and an adhesion receptor during T-cell activation. It is expressed on thymocytes, mature T cells, B-1 B cells, and certain brain cells, and anti-CD6 monoclonal antibodies can enhance T-cell proliferation when combined with accessory cells, PMA, or anti-CD2 mAb.

Picture

SDS-PAGE

2μg (R: reducing condition).

SEC-HPLC

The purity of CD6 His Tag Protein, Human is greater than 90% as determined by SEC-HPLC.

ELISA

Immobilized CD6 His Tag Protein, Human (Cat. No. UA011258) at 5.0μg/mL (100μL/well) can bind ALCAM/CD166 Fc Chimera Protein, Human with EC50 of 2.95-3.49 ng/mL.

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