CD4+T cells were enriched or depleted from BALB/c mouse splenocytes. CD4+ cells were stained with anti-CD4 (clone: GK1.5) Brilliant Violet 421™ and gated on Live+.
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Product Details
Product Specification
| Stability & Storage | Store protected from light at 2 to 8 °C. Do not freeze. |
Background
The CD4 antigen is expressed on most thymocytes and mature T helper cells, on a subset of NKT cells and at lower levels on a subpopulation of dendritic cells. CD4 acts as an accessory molecule in the recognition of MHC class II/peptide complexes by the TCR heterodimer on CD4+ T helper cells. The CD4 antigen is expressed on approximately 90% of thymocytes, 25% of splenocytes, and 55% of lymph node cells.
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Validation Data
