2μg (R: reducing condition, N:non-reducing condition).
CD3 epsilon&CD3 delta Heterodimer Protein, His Tag&Tag Free, Human
CD3 epsilon&CD3 delta Heterodimer Protein, His Tag&Tag Free, Human
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$300 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | CD3E&CD3D |
| Accession | P07766、P04234 |
| Amino Acid Sequence | CD3E: Asp23-Asp126 with His Tag at the C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 20-35kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Guo P, Zhang H, Cao R, Guo H, Zhou X, Pan H, Lin J, Liu Q, Wan Z. Identifying therapeutic targets for erectile dysfunction in the European population using genome-wide Mendelian randomization. Sex Med. 2025 Aug 5;13(4):qfaf056. |
Background
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Components
Protocol
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SDS-PAGE
ELISA
Immobilized CD3 epsilon&CD3 delta Heterodimer Protein, His Tag&Tag Free, Human at 1.0μg/mL (100μL/well) can bind NA/LE Mouse anti-human CD3 mAb (Clone: OKT3)(Cat. No. S0B0009) with EC50 of 3.70-5.27 ng/mL.
