2μg (R: reducing condition, N: non-reducing condition).
CD24 Fc Chimera Protein, Cynomolgus
CD24 Fc Chimera Protein, Cynomolgus
Price:
Regular price
$256 USD
Regular price
Sale price
$256 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Cynomolgus |
| Synonyms | Signal transducer CD24; Ly-52; HAS; Nectadrin; R13-Ag; CD24; CD24A |
| Accession | I7GKK1-1 |
| Amino Acid Sequence | Thr27-Lys54 with Human IgG1 Fc at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 40-55kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & ＞85% by SEC-HPLC |
| Conjugation | Unconjugated |
| Tag | Human IgG1 Fc |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35. |
Background
Cluster of Differentiation 24 (CD24) is a mucin-type glycoprotein linked to the cell membrane via glycosylphosphatidylinositol (GPI). It is expressed on the surface of B-cells. Elevated levels of CD24 expression have been observed in various epithelial cancers, including ovarian, breast, non-small cell lung, prostate, and pancreatic cancers. CD24 plays a role in molecular adhesion and the spread of metastatic tumors, and it serves as a normal receptor for P-selectin. The CD24/P-selectin interaction may be significant in the dissemination of tumor cells by facilitating their interaction with platelets and endothelial cells. Furthermore, CD24 has been considered a potential tumor marker.
Picture
Picture
SDS-PAGE
SEC-HPLC
The purity of CD24 Fc Chimera Protein, Cynomolgus is greater than 85% as determined by SEC-HPLC.
ELISA
Immobilized CD24 Fc Chimera Protein, Cynomolgus (Cat. No. UA011099) at 5.0μg/mL (100μL/well) can bind CD24 Recombinant Rabbit mAb (S-974-13) (Cat. No. S0B0725) with EC50 of 0.15-0.21μg/mL.
