CD19+ cells were enriched or depleted from Human PBMC (human peripheral blood mononuclear cells). Human PBMC were stained with anti-CD19 (clone: HIB19) Brilliant Violet 421™ and gated on Live+.
CD19 Nanobeads, human（RUO）
CD19 Nanobeads, human（RUO）
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Product Details
Product Details
Product Specification
| Application | Positive selection or depletion of cells expressing human CD19 antigen, Isolation or depletion of B cells from peripheral blood mononuclear cells (PBMCs), bodily fluids (e.g. bronchial lavage), or singlecell suspensions from tissue (e.g. lymphoid and tumor |
| Stability & Storage | Store protected from light at +2 to +8 ℃. Do not freeze. |
Background
CD19 Nanobeads have been developed for the separation of human B cells based on the expression of the CD19 antigen. CD19 is a 95–120 kDa glycosylated transmembrane protein that is critically involved in signal transduction processes that regulate development, activation, and differentiation of B lymphocytes. CD19 is expressed on lineage B cells from the early lineage committed pro-B cell stage to the B cell blast stage including most malignant B cells. Expression is down-regulated during the differentiation into plasma cells. Furthermore, CD19 is expressed on follicular dendritic cells.
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Validation Data
