Cardiac Troponins T (cTnT) His Tag, Human
Cardiac Troponins T (cTnT) His Tag, Human
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Troponin T,TnTc,cTnT,TNNT2;Troponin T,TnTc,cTnT,TNNT2 |
| Accession | P45379 |
| Amino Acid Sequence | MHHHHHHDDDDKSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK. |
| Expression System | E.coli |
| Molecular Weight | 28 kDa |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <2EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 20mM Tris-HCl, 100mM NaCl, 1mM EDTA, 2M Urea, pH8.0 |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Cardiac Troponins T (cTnT), Chinese name cardiac troponin T subunit, cardiac troponin I subunit and cardiac troponin C subunit constitute cardiac troponin complex. CTnT is mainly expressed in cardiomyocytes and a small amount in skeletal striated muscle, which can regulate the interaction between actin and myosin mediated by calcium. The content of cTnT in serum can sensitively and specifically reflect myocardial injury, so cTnT is used as a standard biochemical marker for the diagnosis of myocardial infarction and the first biomarker for the diagnosis of acute myocardial infarction (AMI).
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