Product Specification
Host |
Rabbit |
Antigen |
C4d |
Synonyms |
n/a |
Immunogen |
N/A |
Location |
Secreted |
Accession |
P0C0L5 |
Clone Number |
SDT-R021 |
Antibody Type |
Rabbit mAb |
Application |
IHC-P |
Reactivity |
Hu |
Purification |
Protein A |
Concentration |
0.5 mg/ml |
Physical Appearance |
Liquid |
Storage Buffer |
PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
Stability & Storage |
12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
application |
dilution |
species |
IHC-P |
1:500 |
null |
Background
Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system. It serves a number of critical functions in immunity, tolerance, and autoimmunity with the other numerous components. Furthermore, it is a crucial factor in connecting the recognition pathways of the overall system instigated by antibody-antigen (Ab-Ag) complexes to the other effector proteins of the innate immune response.C4d is a degradation product of complement activator. If C4d is high in the tumor of patients, its survival period will be reduced; Complement fragment C4d can be used as a biomarker for early diagnosis and prognosis prediction of lung cancer patients.