1μg (R: reducing condition, N: non-reducing condition).
Biotinylated CEACAM-5/CD66e His&Avi Tag Protein, Human
Biotinylated CEACAM-5/CD66e His&Avi Tag Protein, Human
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$560.00 USD
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Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | CEA, Meconium antigen 100 |
| Accession | P06731 |
| Amino Acid Sequence | Lys35-Ala685, with C-terminal His and Avi Tag |
| Expression System | HEK293 |
| Molecular Weight | 95-130kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4. |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage |
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1.Hammarstrom S. (1999). The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. Seminars in Cancer Biology. 9(2): 67-81. |
Background
The human CEA family has been fully characterized. It comprises 29 genes of which 18 are expressed; 7 belonging to the CEA subgroup and 11 to the pregnancy specific glycoprotein subgroup. CEA is an important tumor marker for colorectal and some other carcinomas. The CEA subgroup members are cell membrane associated and show a complex expression pattern in normal and cancerous tissues with notably CEA showing a selective epithelial expression. Several CEA subgroup members possess cell adhesion properties and the primordial member, biliary glycoprotein, seems to function in signal transduction or regulation of signal transduction possibly in association with other CEA sub-family members.
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SDS-PAGE
ELISA
Immobilized Biotinylated CEACAM-5/CD66e His&Avi Tag, Human (Cat. No. UA010746) at 2 μg/mL on Streptavidin precoated (0.5μg/well) plate, can bind Anti-Human CEA Monoclonal Antibody (Labetuzumab) with EC50 of 2.90-3.65ng/ml.
