Flow cytometric analysis of Mouse Podoplanin expression on C2C12 cells. Cells from the C2C12 (Mouse myoblasts myoblast) were stained with either Biotin Syrian Hamster IgG Isotype Control (black line histogram) or SDT Biotin Syrian Hamster Anti-Mouse Podoplanin Antibody (red line histogram) at 2 μl/test. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.
Biotin Syrian Hamster Anti-Mouse Podoplanin Antibody (8.1.1)
Biotin Syrian Hamster Anti-Mouse Podoplanin Antibody (8.1.1)
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Product Details
Product Details
Product Specification
| Host | Syrian Hamster |
| Antigen | Podoplanin |
| Synonyms | Glycoprotein 38 (Gp38); OTS-8; PA2.26 antigen; Transmembrane glycoprotein E11 (E11); Gp38; Ots8; Pdpn |
| Location | Cell membrane |
| Accession | Q62011 |
| Clone Number | 8.1.1 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C2C12 |
| Purification | Protein G |
| Concentration | 0.5 mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.09% sodium azide |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 1μg per million cells in 100μl volume | Ms |
Background
Podoplanin is a small, mucin-like transmembrane glycoprotein that plays diverse roles in both physiological and pathological processes. Initially identified in podocytes of the kidney, it is also expressed in various tissues, including the brain, heart, lungs, and lymphatic endothelium. Podoplanin is a key marker for lymphatic vessels and is involved in lymphangiogenesis, embryonic development, and platelet aggregation. In cancer, its expression is associated with tumor invasion and metastasis, making it a potential therapeutic target. Additionally, podoplanin has been implicated in neurological disorders, inflammation, and immune responses, highlighting its multifaceted importance in health and disease.
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