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Biotin Mouse Anti-Human CD138 Antibody (S-R553)

Biotin Mouse Anti-Human CD138 Antibody (S-R553)

Catalog Number: S0B8576 Application: FCM Reactivity: Human Conjugation: Biotin Brand: Starter
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Regular price $60 USD
Regular price Sale price $60 USD
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Product Details

Product Specification


Host Mouse
Antigen CD138
Synonyms Syndecan-1; SYND1; SDC; SDC1
Location Membrane
Accession P18827
Clone Number S-R553
Antibody Type Mouse mAb
Isotype IgG1
Application FCM
Reactivity Hu
Positive Sample U266B1
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD138, also known as syndecan-1, is a transmembrane heparan sulfate proteoglycan that plays a crucial role in cell adhesion, migration, and signaling. It is predominantly expressed on the surface of plasma cells and certain epithelial cells. In plasma cells, CD138 serves as a valuable marker for their identification and isolation, aiding in the diagnosis and study of plasma cell disorders such as multiple myomael. On epithelial cells, it contributes to the maintenance of cell structure and function by interacting with extracellular matrix components and growth factors. Additionally, CD138 is involved in various biological processes including wound healing, inflammation, and cancer progression. Its ability to bind and modulate the activity of numerous proteins makes it an important factor in cellular communication and regulation.

Picture

FC

Flow cytometric analysis of Human CD138 expression on U266B1 cells. Cells from the U266B1 (Human multiple myeloma B lymphocyte, Right) or Jurkat (Human T cell leukemia T lymphocyte, Left) was stained with either Biotin Mouse IgG1 Isotype Control (Black line histogram) or SDT Biotin Mouse Anti-Human CD138 Antibody (Red line histogram) at 5 μl/test followed by Sav-PE. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.