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Biotin Armenian hamster Anti-Mouse/Rat CD61 Antibody (2C9.G2)

Biotin Armenian hamster Anti-Mouse/Rat CD61 Antibody (2C9.G2)

Catalog Number: S0B8660 Application: FCM Reactivity: Ms, Rt Conjugation: Biotin Brand: Starter
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Product Details

Product Specification


Host Armenian hamster
Antigen CD61
Synonyms Integrin beta-3; Platelet membrane glycoprotein IIIa (GPIIIa); Itgb3
Location Cell membrane
Accession O54890
Clone Number 2C9.G2
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Ms, Rt
Positive Sample C57BL/6 mouse bone marrow
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Ms, Rt

Background

CD61, also known as integrin β3, is a 90-92 kDa type I transmembrane glycoprotein that dimerizes with integrin αIIb (CD41) to form the platelet fibrinogen receptor GPIIb/IIIa or with integrin αV (CD51) to form the vitronectin receptor, and plays a pivotal role in platelet aggregation, clot retraction, angiogenesis, and the adhesion and migration of osteoclasts, smooth muscle cells and tumor cells via recognition of RGD motifs in ligands such as fibrinogen, fibronectin, von Willebrand factor, vitronectin and thrombospondin.

Picture

FC

Flow cytometric analysis of CD61 expression on C57BL/6 mouse bone marrow. C57BL/6 mouse bone marrow cells were stained with Phycoerythrin Rat Anti-Mouse TER-119 Antibody and either Biotin Armenian Hamster IgG Isotype Control (left panel) or SDT Biotin Armenian Hamster Anti-Mouse CD61 Antibody (right panel) at 5μl/test followed by Sav-iFluor 488. Flow cytometry and data analysis were performed using Agilent NovoCyte Quanteon and FlowJo™ software.