Flow cytometric analysis of Mouse CD196 expression on C57BL/6 mouse splenocytes. C57BL/6 mouse splenocytes were stained with Pacific Blue™ Rat Anti-Mouse CD45R/B220 Antibody and either Biotin Armenian hamster IgG Isotype Control (Left panel) or SDT Biotin Armenian hamster Anti-Mouse CD196 Antibody (Right panel) at 5μl/test followed by Sav-PE. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.
Biotin Armenian hamster Anti-Mouse CD196 Antibody (S-R621)
Biotin Armenian hamster Anti-Mouse CD196 Antibody (S-R621)
Price:
Regular price
$111.00 SGD
Regular price
Sale price
$111.00 SGD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Host | Armenian hamster |
| Antigen | CD196 |
| Synonyms | C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; KY411; Cmkbr6; Ccr6 |
| Location | Cell membrane |
| Accession | O54689 |
| Clone Number | S-R621 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Biotin |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD196, also known as CCR6, is a ~42 kDa G protein-coupled seven-transmembrane chemokine receptor expressed on immature dendritic cells, memory T and B cells, NK cells and Langerhans cells; it binds the unique ligand CCL20 (MIP-3α), triggering calcium signaling that directs chemotactic recruitment of these cells to epithelial and inflamed tissues, thereby orchestrating mucosal immunity, Th17 and regulatory T-cell differentiation, B-lineage maturation, and pathogenic inflammatory circuits in diseases such as psoriasis, rheumatoid arthritis and inflammatory bowel disease.
Picture
Picture
FC
