1μg (R: reducing condition, N: non-reducing condition).
APLP2/Amyloid-like protein 2 His Tag Protein, Human
APLP2/Amyloid-like protein 2 His Tag Protein, Human
Price:
Regular price
$296 USD
Regular price
Sale price
$296 USD
Unit price
per
For shipping services or bulk orders, you may request a quotation.
Secure checkout with
View full details
Product Details
Product Details
Product Specification
| Species | Human |
| Synonyms | Amyloid beta precursor like protein 2, APLP2, APPH, CDEBP, APPL2 |
| Accession | Q06481-1 |
| Amino Acid Sequence | Gly32-Ser692 with His Tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 80-100kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & SEC-HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Wang X, et al. (2018) Aplp2 modulates jnk-dependent cell migration in drosophila. Biomed Res Int 2018 7469714. |
Background
YWK-II protein/APLP2 is a member of an evolutionarily conserved APP family that includes amyloid precursor protein (APP) and amyloid precursor-like protein-1 (APLP1). YWK-II/APLP2 functions as a novel G(0)-protein-coupled receptor for Müllerian inhibiting substance (MIS) in cell survival. Human leukocyte antigen-B-associated transcript 3 (Bat3), an important regulator involved in apoptosis, can interact with YWK-II/APLP2 and enhance its stability by reducing its ubiquitylation and degradation by the ubiquitin-proteasome system. May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Picture
Picture
SDS-PAGE
SEC-HPLC
The purity of APLP2/Amyloid-like protein 2 His Tag Protein, Human is greater than 95% as determined by SEC-HPLC.
