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APC Mouse Anti-Human CD42b Antibody (S-935-7)

APC Mouse Anti-Human CD42b Antibody (S-935-7)

Catalog Number: S0B8133 Application: FCM Reactivity: Human Conjugation: APC Brand: Starter
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$216.00 SGD
$216.00 SGD
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Product Details

Product Specification


Host Mouse
Antigen CD42b
Synonyms Platelet glycoprotein Ib alpha chain; GP-Ib alpha; GPIb-alpha; GPIbA; Glycoprotein Ibalpha; Antigen CD42b-alpha; GP1BA
Accession P07359
Clone Number S-935-7
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample Human peripheral blood platelets
Purification Protein G
Concentration 0.2 mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD42b, also known as glycoprotein Ib alpha (GPIbα), is a type I transmembrane glycoprotein expressed on platelets and megakaryocytes. It is a key component of the GPIb-IX-V receptor complex, which plays a critical role in platelet adhesion and thrombus formation by binding to von Willebrand factor (vWF) at sites of vascular injury. CD42b interacts with various molecules, including thrombin, coagulation factors XI and XII, and P-selectin, contributing to hemostasis and thrombosis. Mutations or polymorphisms in CD42b are associated with diseases such as Bernard-Soulier syndrome and platelet-type von Willebrand disease.

Picture

FC

Flow cytometric analysis of Human CD42b expression on human peripheral blood platelets. Human peripheral blood platelets were stained with either APC Mouse IgG1, κ Isotype Control (Black line histogram) or SDT APC Mouse Anti-Human CD42b Antibody (Red line histogram) at 5 μl/test. Flow cytometry and data analysis were performed using BD FACSymphony™ A1 and FlowJo™ software.