Flow cytometric analysis of human peripheral blood leukocytes labelling Integrin alpha-4 antibody at 1μg / (Right panel) compared with a Human IgG Isotype Control / (Left panel). Goat Anti-Human IgG Alexa Fluor® 488 was used as the secondary antibody.
Anti-CD49d Monoclonal Antibody (Natalizumab)
Anti-CD49d Monoclonal Antibody (Natalizumab)
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$300 USD
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Product Details
Product Details
Product Specification
| Host | Human |
| Antigen | Integrin alpha-4 |
| Accession | P13612 |
| Clone Number | S-SC023 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG4,k |
| Application | Blocking of Integrin alpha-4 signaling Functional assays |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Natalizumab, is a monoclonal antibody which targets a protein called α4β1 integrin on white blood cells involved in inflammation. By attaching to integrin, natalizumab is thought to stop white blood cells from entering the brain and spinal cord tissue, thereby reducing inflammation and the resulting nerve damage.
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