Product Details
Product Details
Product Specification
Host | Human |
Synonyms | Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor (ODF), Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNFSF11, OPGL, CD254, TRANCE |
Accession | O14788 |
Clone Number | S-SC009 |
Antibody Type | Recombinant mAb |
Isotype | IgG1,k |
Application | Blocking of RANKL signaling Functional assays |
Purification | Protein A |
Concentration | 2 mg/ml |
Endotoxin | <1EU/mg |
Conjugation | Unconjugated |
Physical Appearance | Liquid |
Storage Buffer | PBS pH7.4, containing no preservative |
Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Denosumab is a human monoclonal antibody against RANKL used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.
