Immobilized RANK L/TNFSF11(182aa) Protein, Human(UA040336) can bind Denosumab. The EC50 for this effect is 0.9133 ng/mL.
Anti-CD254 Monoclonal Antibody(Denosumab)
Anti-CD254 Monoclonal Antibody(Denosumab)
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$285 USD
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$285 USD
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Product Details
Product Details
Product Specification
| Host | Human |
| Synonyms | Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor (ODF), Osteoprotegerin ligand, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNFSF11, OPGL, CD254, TRANCE |
| Accession | O14788 |
| Clone Number | S-SC009 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG1,k |
| Application | Blocking of RANKL signaling Functional assays |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Background
Denosumab is a human monoclonal antibody against RANKL used for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone.
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